Endocrine Abstracts

Cognitive dysfunctions, observed in the course of thyroid diseases (hyper- and hypothyroidism), have – in the recent years – been the subject of interest for many research teams. Even mild disorders of thyroid functionality are associated with hormone concentration changes which affect the general mood and cognitive functions. The efficiency of cognitive functions, which allow the man’s adaptation to environment al conditions, is determined by the activities of ...

Introduction: Diabetic retinopathy and lower limbs and heart muscle perfusion disturbances are important complications in diabetes. Early recognition of diabetic retinopathy and acroangiopathic disturbances reduce the complications frequency.Aim: Correlation of lower limbs and heart muscle perfusion disturbances and diabetic retinopathy progression level in patients with diabetes 2. The assessment to what extend diabetic retinopathy progression level may...

Radiation therapy is used in the treatment of pituitary adenomas, especially in failures of neurosurgery and pharmacotherapy to reduce the size of adenomas and normalize their hypersecretion. Conventional fractionated radiotherapy has achieved good results, but only after a long latency, with considerable postradiation morbidity and with very frequent appearance of hypopituitarism. The focal stereotactic targeting allowed by Leksell gamma-knife (LGK) was supposed to decrease t...

Vertebral morphometric X-ray absorptiometry (MXA) is a new tool developed to evaluate the presence of vertebral deformities. Low dose of radiation, fan-beam and the centerline scan technique are believes more advantageous than the classic morphometry using conventional lateral radiograms. We assessed the prevalence of vertebral fractures by MXA in adult population of &Lstrok;ód&zacute; region as a part of Polish population studied in EPOLOS epidemiological study.<p cl...

Introduction: The objective of the research was to determine the predictive value of the most probable etiopathogenetic factors contributing to the development and progression of gastric dysfunction in patients with type 2 diabetes. Only 5% of type 1 and 1% of type 2 diabetic combine the delay of gastric emptying (DGE) with typical gastroparesis symptoms. Systematic review of risk factors of development and progression symptoms of diabetic gastroparesis (DG). Results presented...

Acromegaly is caused by excessive growth hormone (GH) secretion from pituitary adenomas. Transphenoidal surgery is the first-choice treatment, but new drug therapies (e.g. somatostatin analogs, SSA) offer promising avenues for medical treatment. Complementary diagnostic tools may assist this strategy, helping to refine drug choice. Here, we investigate the associations between postsurgical radiological features and molecular phenotype of pituitary tumors from acromegalic patie...

Introduction: The role of the pineal gland and its hormone, melatonin, in the regulation of hypothalamo-adenohypophysial system activity is well known. At the same time, studies of the circadian rhythm of melatonin secretion in patients with pituitary adenomas are few in number, because the evaluation of pineal activity is not generally included in the clinical investigation of patients with pituitary tumors.Aim: The present study analyzed the circadian ...

Primary hyperparathyroidism (PHPT) is a complex endoctinopathy that involves parathyroid glands which secreting too much parathyroid hormone and due to causes hypercalcemia effecting different organs and leading to significant quality of life (QoL) impairment. QoL assessment before and after surgery in patients with PHTP may be useful for comprehensive evaluation of the treatment effect, as well as for monitoring of the patient’ condition after surgery, including in real ...

Aims: We aimed to evaluate the relationship between glycosylated hemoglobin (HbA1c), time-in-range (TIR), Glucose Management Index (GMI) and coefficient of variation (CV) in a cohort of adult patients with type 1 diabetes (T1DM) and flash glucose monitoring (FGM).Material and methods: Cross-sectional study of patients with T1DM who FGM from Córdoba, Spain. Demographic and analytical data were collected. Glucose metrics and engagement statistics (adj...

Introduction: Eating disorders (ED) are prevalent psychiatric conditions with significant nutritional implications, posing a risk of life-threatening illness for patients. The chronic and recurrent nature of these disorders, along with normal laboratory test results, present challenges in their management and ongoing monitoring, which typically focuses on weight changes. Techniques like determining the phase angle using bioimpedance analysis or conducting functional muscle tes...